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Of note, enhanced risk of multiple sclerosis has been associated with variations in the circadian genes ARNTL/BMAL1 and CLOCK ( Does an intrinsic circadian rhythm indwell the Schwann cells

Figure 4 Autophagy induction has been proposed to be the primordial function of cGAS-STING signaling before interferon induction evolved

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Glycine and serine are principal donors of single-carbon units to the one-carbon metabolism cycle, a key metabolic process in the human body that involves folate-mediated movement of single-carbon units for methylation, redox, and biosynthetic reactions 15

Proc Natl Acad Sci USA (2006) 103(33):124938