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MAPK signaling MAPKs are a family of highly conserved pathways, including three major subfamilies, the extracellular signal-regulated kinases (ERK), c-Jun NH2-terminal kinase (JNK), and p38 isoforms, 135 allowing the cells to respond to multiple extracellular stimuli, such as hormones, growth factors, inflammatory cytokines, and other stresses

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"Melanotan is a synthetic hormone which is injected via a needle under the skin to stimulate the pigment cells in your body to produce more melanin, which in turn gives you a tan," says Dr Ross Perry, skin cancer expert and Medical Director of Cosmedics

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