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The resulting suboptimal homeostasis of glutathione (GSH) results in a decreased capacity to minimize oxidative stress, which is associated with poor outcomes during aging, inflammation and in multiple disease states.

doi: 10.1038/nri2448 24 ZhouJTangZGaoSLiCFengYZhouX

Here, we studied the cellular sites of DPP-4 expression required for control of lipid metabolism in mice using gut-selective versus systemic inhibitory concentrations of the DPP4i sitagliptin (19, 20)

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