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There is no Phase 1 trial, no toxicology dossier, no characterized human dose, and no adverse-event registry

Acknowledgements The authors thank Dr Nicholas Vierra, University of Utah, for the SPHKAP antibodies

Refined structure of glutathione reductase at 1.54 resolution

This is a new mechanism whereby locally synthesized melatonin may protect against neurodegeneration

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Overall, these results suggest that oral GSH supplementation can effectively increase body stores of GSH and may also reduce oxidative stress and enhance certain aspects of immune function, particularly NK cell cytotoxicity