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Other frequent issues: shaking instead of swirling, using the wrong diluent (sterile water when the product calls for bacteriostatic), losing the reconstitution date, or top-mixing additional water into a partly-used vial without recalculating

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Tagrisso is also approved to treat NSCLC with EGFR mutations in the first line metastatic setting as a monotherapy and in combination with chemotherapy, and as an adjuvant treatment for early-stage disease

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