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The peptide itself is a GLP-1 receptor agonist

27 A total of 703 participants with uncontrolled T2DM (A1C of 7.09.5%) were randomized into four treatment groups that included a daily dose of either 3 mg, 7 mg, or 14 mg of oral semaglutide or placebo for 26 weeks

Young agrees that lower inflammation could be part of the effect of GLP-1s

Fourth, to assess the influence of unmeasured confounding, the E value was calculated based on the estimated HR for DR [30]