PGE2, prostaglandin E2
Think lean proteins, fruits, vegetables and whole grains, says Jaeger
DHODH activity is essential for proliferating cells owing to their increased demand for nucleotides, and DHODH inhibition has long been studied as a therapeutic strategy in autoimmune diseases (for example, via leflunomide) and cancer, where it can lead to cell cycle arrest, DNA damage and replication stress 42,44,45
Low IGF-1, which is sensitive to nutrient intake and associated with organ growth/differentiation, slows down growth in undernourished children [59, 60]
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