GPs can prescribe B12 injections following appropriate investigation, which should include: Full blood count to identify macrocytic anaemia Serum B12 and folate levels to confirm deficiency (using laboratory-specific reference ranges) Methylmalonic acid and/or homocysteine when B12 results are borderline Intrinsic factor antibodies if pernicious anaemia is suspected Additional tests depending on clinical presentation (e.g., thyroid function, coeliac serology) When both B12 and folate deficiency are present, B12 should be replaced before folate to avoid precipitating subacute combined degeneration of the spinal cord
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This medicine requires a valid prescription from a licensed physician
This injection is typically prescribed to potentially prevent or treat deficiencies of these B vitamins and to support patients with conditions like malabsorption, increased metabolic demand, or recovery from illness where oral vitamin intake is insufficient
Additionally, immobilizing the affected limb should be avoided to enhance lymphatic drainage