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Compared to the control AB(WT) fish, the LMNA (WT) and the LMNA mutant transgenic fish (except LMNA (W520G) because no fish survived after F0) showed significantly higher levels of LMNA mRNA expression (Fig

That size cutoff is the entire pharmacological bet, because small peptides are the part of a neurotrophic signal that might actually cross the blood-brain barrier, the gatekeeping wall that blocks the bodys own large growth factors from reaching the brain from the bloodstream

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