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Description

Peripheral GLP-1 or GLP-1RAs may interact with appetite-regulating regions of the brain via gaps in the blood-brain barrier, via tanycyte uptake, or indirectly via the nodose ganglia

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3841 Unresolved Role of GLP-1RAs in Heart Failure with Reduced Ejection Fraction Unlike the positive results reported for GLP-1RAs in HFpEF, findings from dedicated trials in heart failure with reduced ejection fraction (HFrEF) report neutral findings

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