Reconstitution math for a 5 mg vial: 1 ml diluent 5 mg/ml (high concentration) 2 ml diluent 2.5 mg/ml (common research reference) 5 ml diluent 1 mg/ml (for small-volume aliquots) Reconstitution procedure: Swab vial rubber seal with alcohol wipe
What's more, the drugs were never approved for that use
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Any cloudiness, even slight, indicates protein aggregation
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(The cost of B12 is pennies but the time for nurses to give the injection appears to be the saving here.) Some practices are enclosing diet sheets for patients to learn how to make sure they are eating foods containing B12