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The IRR is a heteroreceptor complex formed by the erythropoietin receptor and the beta-common receptor (CD131)

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In ferroptosis, SLC7A11 and GSH depletion lead to iron-dependent ROS accumulation ( Ferroptosis and alzheimers disease Iron homeostasis and alzheimers disease Regulation of iron homeostasis is important for maintaining normal brain function, and dysregulation of iron homeostasis in the brain can lead to oxidative stress and inflammatory responses, resulting in cell damage and ultimately neurodegenerative diseases

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Glutathione (GSH) levels in lung homogenates were determined enzymatically, and NO detection was performed using Griess reagent [1]

48 Vitamins C and E can enhance catalase activity and decrease oxidative stress