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rare complications include allergic reactions and hypokalaemia during treatment of severe anaemia

AOD 9604 has a substantial history of clinical study

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In cell culture and rodent assays, MOTS-c enhances glucose uptake, modulates AMPK pathways, and supports resilience under metabolic stress

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Unlike GLP-1 agonists such as semaglutide or tirzepatide, which work primarily through appetite suppression, AOD-9604 directly enhances fat metabolism at the cellular level through beta-3 adrenergic receptor modulation