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Compounded semaglutide and compounded tirzepatide have become increasingly popular precisely because of these benefits

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In their exclusion criteria, they note patients cannot be on a GLP-1 in the 90 days prior to screening

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Combining GLP-1RAs with anti-VEGF agents or IOP-lowering drugs may enhance efficacy but pose unresolved challenges

Discontinuation Rates Due to GI Adverse Events Stomach pain severe enough to cause participants to leave clinical trials is the most meaningful measure of GI tolerability