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Indeed, cellular DNA precursor pools, even during S phase, are typically only a small fraction of the concentration of RNA precursor pools (Rottgen and Rabes, 1989

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In canonical Wnt/-catenin signaling, the secreted Wnt ligands bind with the Frizzled receptor, which further inactivates glycogen synthase kinase-3 (GSK-3), which is an enzyme responsible for the ubiquitination-mediated degradation of -catenin 4,5