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What are the side effects and contraindications

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ER stress is essentially a protective mechanism that reduces new protein production to alleviate the ER burden and prevent the accumulation of unfolded proteins (55)

This allows patients to receive comprehensive information about the effectiveness of these medications, as well as advice about possible side effects

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EPN-1::GFP is readily visualized in all four blastomeres at the four-cell stage of embryogenesis, and RNAi efficiently reduces EPN-1::GFP to undetectable levels at the 4-cell stage (Figure 1B, left)