5-amino-1MQ stimulates the growth of nicotinamide adenine dinucleotide (NAD +), a cofactor that is crucial for cellular metabolism, thereby increasing the metabolic rate and activating a gene called sirtuin-1 (SIRT1)
Additionally, the GH release triggers hepatocytes to secrete IGF-1 which assists in the regulation of overall growth, cell death, and lipolysis [1]
Every 4 weeks for the first 12 weeks, then every 12 weeks thereafter
5-Amino-1MQ's mechanism centers on NNMT inhibition: NNMT inhibition : Selectively blocks NNMT with an IC50 of approximately 1.2 microM
Each component is studied in experimental systems for roles relevant to tissue repair and regenerative signaling pathways
They often start with a higher dose, then get smaller doses based on how they do