If you are very B12 deficient you will notice an increase in energy and a reduction in symptoms of tingling, numbness, or twitching/zaps within 24 hours
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Allow the initial dose to establish baseline response before making adjustments
High-dose oral therapy (10002000 micrograms daily) can effectively treat deficiency even in those with impaired intrinsic factor-mediated absorption, relying on passive diffusion
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Vitamin b12 deficiency symptoms can include peripheral neuropathy (numbness and tingling in the hands and feet), problems with balance and coordination, memory loss, trouble concentrating, changes in mental status, and depression, among other symptoms