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With the advance of combination therapy, the combination of targeted IGFs and other technologies for the treatment of tumors has shown advantages, which not only increase the efficacy but also effectively prevent the occurrence of drug resistance
The GSSG-dependent oxidation of roGFP2 by fused PfGrx variants is two to three orders of magnitude faster than the oxidation by unfused PfGrx(SSG) variants and more than seven orders of magnitude faster than the uncatalyzed reaction with GSSG (Table 1)
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