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These findings suggest that DMF presents anti-inflammatory and oxidative/ferroptosis stress defense effects in SCD mice

It specifically targets GH release

Impaired barrier function and immunity in the colon of aldo-keto reductase 1B8 deficient mice

Results Oxidative and antioxidative status in cardiac tissue Antioxidant enzyme levels in cardiac tissue The analysis of antioxidant and oxidant parameters in various experimental groups revealed significant differences in TAS levels (Fig

Notably, this dual-pathway mechanism is conserved in clinically relevant human liver samples and organoids

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