Were not just trying to put out a fire
498 Studies on Tp IscR reveal that different homologues of IscR employ different ligand sets, despite what is likely the same function in surveilling the FeS status of the organism (Figure 17B)
10.3390/ijms221910651 13 CastellanoS.LobanovA
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Glutathione levels and BAX activation during apoptosis due to oxidative stress in cells expressing wild-type and mutant cystic fibrosis transmembrane conductance regulator
Hepatic effects that are considered adverse include death, abnormal clinical chemistry parameters, obvious functional organ impairment, DNA and mitochondrial alteration, glutathione depletion, hepatocyte necrosis, enhanced replicative DNA synthesis, generation of reactive oxygen species, and increased peroxisome proliferation (in rodents) (Williams and Iatropoulos 2002)
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