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Orthotopic xenografts were generated by implanting 2.5 million MDA-MB-231 cells in 100 L phosphate-buffered saline (PBS) mixed with 100 L growth factor-reduced Matrigel (Corning) bilaterally into the fourth inguinal fat pad of four- to six-week-old female NOD

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In a 24-week randomized placebo-controlled trial, volunteers with elevated uric acid levels who received twice-daily capsules of 500 mg T