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Global burden of cardiovascular diseases and risk factors, 19902019: Update from the GBD 2019 study

Tirzepatide once weekly for the treatment of obesity in people with type 2 diabetes (SURMOUNT-2): A double-blind, randomised, multicentre, placebo-controlled, phase 3 trial

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In erastin- or RSL3-induced ferroptosis in hepatocellular carcinoma cells, IFN- triggers the JAK-STAT-IRF1 axis and inhibits transcription of the System Xc subunits SLC3A2 and SLC7A11 (122, 123)

However, these findings are still awaiting further confirmation

NO contributes to this process by promoting the production of vascular endothelial growth factor (VEGF) and activating signaling pathways such as cGMP, both of which play roles in vascular development (3234)