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Topoisomerase IIbeta mediated DNA double-strand breaks: implications in doxorubicin cardiotoxicity and prevention by dexrazoxane

Lambadiari V, Pavlidis G, Kousathana F, Varoudi M, Vlastos D, Maratou E, Georgiou D, Andreadou I, Parissis J, Triantafyllidi H, et al

Basic & Clin

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T-1 regulates the immune response by primarily acting on cells of the innate immune system, therefore acting as an endogenous regulator of both inflammatory and adaptive immune responses