Additionally, semaglutide suppresses glucagon secretion, slows gastric emptying, and promotes satiety, which collectively improve glycaemic control and often lead to weight loss
The medication demonstrates substantial efficacy in reducing hemoglobin A1c levels and promoting weight loss, with reductions of up to 21% of body weight observed in clinical trials of patients with obesity without diabetes, and approximately 12-15% in those with type 2 diabetes
Inflammatory markers C-reactive protein (CRP) and other inflammatory markers tend to decrease with tirzepatide use, largely driven by weight loss and improved metabolic function
for others with very high BMI and complications, surgery may remain the most appropriate choice
Eat Smaller, More Frequent Meals Instead of three large meals, opt for five to six smaller meals throughout the day
Most side effects can be managed without stopping treatment