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Data from preclinical models in mice and human data also suggest that the tolerability and efficacy of GLP-1 agonists vary with the hormonal cycle and that higher circulating estrogen levels are associated with a heightened risk of nausea and vomiting

Side Effects to Consider No medication is without side effects

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When people take highly addictive drugs like cocaine, it causes an increase in dopamine levels in certain parts of the brain that are involved in reward and reinforcement

Foods that are high in calories but low in nutritional value and fibre tend to be less satiating and may reduce the effectiveness of appetite-suppressing medication

Consistent with earlier studies using NVP DPP728, insulin:glucose ratios were improved in DPP4 inhibitor-treated subjects