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doi:10.1097/CM9.0000000000002431

Phase 3 trial of lumasiran for primary hyperoxaluria type 1: a new RNAi therapeutic in infants and young children

The differential diagnosis is broad because symptoms can be due to gastrointestinal (malrotation, gastroparesis), intracranial (intracranial masses, hydrocephaly), or abdominal (renal colic) disorders, or to metabolic (fatty acid oxidation or urea cycle disorders, mitochondrial dysfunction) or drug/toxin (CHS) alterations.77 Laboratory, radiographic, and endoscopic tests detect a substantial number of these differential diagnoses

Its a common concern for many women post-pregnancy and has led many to consider undergoing cosmetic surgery options like liposuction and tummy tuck surgery

It is postulated that l-carnitine facilitates the transfer of activated long-chain fatty acids into the mitochondria as an acyl-carnitine ester for -oxidation 11

GLP-1 drugs replicate these effects, helping patients with diabetes and those struggling with weight gain