Mentioned in: Cryotherapy, Sunscreens Gale Encyclopedia of Medicine
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In animals, moderate concentrations of taurine activate the glycine receptor, while high concentrations act as a weak GABA-A receptor agonist in certain brain regions
The immunogenicity risk assessment of TPT and selected peptide-related impurities was performed using three orthogonal methods, as previously described ( in silico tools (EpiMatrix, ClustiMer, and JanusMatrix) ( in vitro human leukocyte antigen (HLA) binding assays were conducted to evaluate differences in HLA binding affinity of TPT and its impurities across common HLA-DR allele supertypes
A thorough medication review is necessary to identify potential interactions and adjust doses of other glucose-lowering medications, particularly insulin or sulfonylureas, to minimise hypoglycaemia risk
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