Contact your GP or prescribing clinician if you experience cold intolerance accompanied by other symptoms that might suggest thyroid dysfunction, such as: Extreme fatigue or weakness that interferes with daily activities Unexplained weight gain or cessation of weight loss despite adherence to treatment Significant hair loss or changes in hair texture Persistent constipation unresponsive to usual measures Dry, flaky skin or changes in skin texture Muscle aches, cramps, or weakness Slowed heart rate Depression or significant mood changes Cognitive difficulties, including memory problems or difficulty concentrating These symptoms could indicate hypothyroidism , which requires investigation through thyroid function tests (TSH, free T4)
Many denials are paperwork problems that can be fixed with proper documentation
For international destinations, this is more complex and should be arranged before departure
If you experience these changes, view them as a sign that the medication is actively altering your metabolic rate and gastric motility as intended
As therapists, our most direct contributions are recognizing the signs of hypoglycemia, understanding how exercise amplifies or interacts with insulin's glucose-lowering effects, and educating patients about monitoring and safety
GLP-1s do not cause any physiological dependence, and once-weekly GLP-1 medications, like Wegovy or Zepbound, have a long half-life in patients bodies, he says