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GLP-1 receptors exist in the area postrema of the brainstem, the region that controls the vomit reflex

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This may include any of the following symptoms: Severe itching or a severe rash A red patch that tracks along the skin Peeling or blistering skin (with or without a fever) A swollen face, lips, tongue, mouth or throat Difficulty breathing, talking or swallowing A very rapid heartbeat A tight chest Wheezing Feeling dizzy or fainting On rare occasions, Wegovy can cause a skin sensitivity reaction that feels like burning or tingling

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However, you need to compare them to the baseline risk for the population taking these medications

Most people learn how to self-inject semaglutide at home, though regular follow-up with a medical professional is essential to monitor progress and adjust dosage as needed