2.3.2 GPX4: a core regulator of ferroptosis Ferroptosis is related to the inactivation of GPX4 (70)
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As a major intracellular antioxidant, it directly neutralises reactive oxygen species (ROS) and free radicals that accumulate during normal metabolism and are elevated in fatty liver disease
Your body continuously produces and uses glutathione, so dietary changes can begin supporting glutathione levels within days
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Reactive oxygen species (ROS) levels KGN cells were incubated in serum-free DMEM using 3 M C11-BODIPY 581/591 (Invitrogen), washed three times with serum-free medium, trypsinized, resuspended in PBS, and detected by flow cytometry