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In particular, TMAO was shown to trigger platelet activation and thrombosis via increasing the platelet responsiveness by enhancing stimulus (ADP, collagen, thrombin, or arachidonic acid)-dependent mobilization of intracellular Ca 2+ stores in platelets (Zhu et al., 2016
The role of transcription factor 7-like 2 in metabolic disorders
doi: 10.3390/cells12172178 147 Ben-DavidMAElkayamRGelernterIPfefferRM
Multiple studies done by Lenzi A et al (a research group in Italy) which were published in The Oxford Journal of Human Reproduction, Frontiers in BioScience, Archives of Andrology, and Contraception , came to the following conclusions in regards to sperm, oxidative stress (inflammation), and glutathione
Ji, H., Bradley, T