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Antihistamines like hydroxyzine and diphenhydramine are frequently employed as initial treatments for pruritus due to their safety and availability

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Regarding the regulation of T cell polarization, HMGB1 induces the shift of CD4 + T cells towards the Th2 phenotype, resulting in a reduction in IFN secretion and facilitating Treg proliferation

Foudah AI, Alam P, Shakeel F, Alam A, Salkini MA, Alshehri S (2022) A simple, cost-effective, and green HPTLC method for the estimation of ascorbic acid in solvent and ultrasound-assisted extracts of Phyllanthus emblica , Capsicum annuum , and Psidium guajava

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