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Tamoxifens tissue-selective agonism preserves estrogenic benefits in bone and liver, while antagonizing estrogen where it's harmful. Jordan, Journal of Steroid Biochemistry and Molecular Biology Tamoxifens Tissue-Specific Actions One of the most unique aspects of Tamoxifen is that it doesnt behave the same way in every part of the body

We will also talk about how and when doctors decide to give it to people

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As you move from 2.5 mg to higher strengths, the gastric delay can be more pronounced, leading to inconsistent levels of contraceptive hormones in your bloodstream

54 In contrast, IR and compensatory hyperinsulinemia cause abnormal activation of ovarian primordial follicles, increasing the sensitivity of pre-antral follicles to follicle-stimulating hormone (FSH), leading to excessive follicle recruitment and ultimately resulting in polycystic ovary-like changes