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What the 2025 Gastroenterology Metaanalysis Found The systematic review and metaanalysis (DOI: 10.1053/j.gastro.2025.06.003) evaluated safety outcomes across randomized trials and realworld studies of GLP1 RAs

While individual results will vary, these are consistent with what might be expected when appetite is reduced and satiety is improved, especially if combined with resistance training and adequate protein intake to preserve muscle

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This means your body usually has plenty of glutamate and glycine, but cysteine is harder to come by