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Zepbound and Mounjaro (tirzepatide): why the FDA put a warning on the label Tirzepatide has 2 active ingredients: GLP-1 / GIP dual agonists and the FDA labels for both Mounjaro (the diabetes formulation) and Zepbound (the chronic-weight-management formulation) carry an explicit drug-interaction note about oral hormonal contraceptives

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doi: 10.1038/nrneph.2017.126