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J Am Chem Soc (2004) 126(40):127367

The salt content can interfere with peptide stability and cause precipitation in some cases

Chronic Conditions: Individuals with chronic conditions that affect B12 absorption, such as pernicious anemia or gastrointestinal disorders, may need regular injections throughout their lives

The absence of guidance from professional societies is itself a data point

This method is often used at the start of treatment or for severe symptoms

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