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According to the manufacturers of Ozempic and Wegovy, the main common side effects may include: Nausea, vomiting, and diarrhea that could lead to an acute kidney injury Dizziness Rapid heart rate Headaches Hypoglycemia Allergic reactions to the medication Abdominal pain Shortness of breath Severe hypoglycemia Blurred vision Severe rash Slurred speech Hoarse voice Other minor side effects to watch out for include a rise in resting heart rate, a decrease in heart rate variability, and mood changes (like anxiety and depression)

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While the complete results of the study have not yet been published, an initial press release in 2024 indicated that tirzepatide reduced the relative risk for the composite endpoint (HF urgent visit or hospitalization, oral diuretic intensification, or cardiovascular death) by 38%

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