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Biological actions of GLP-1, source: reference [1] Biopharma PEG Evolution of GLP 1 GLP-1RAs Currently, there are nine GLP-1RAs approved for marketing worldwide (Table 1), mainly for the treatment of diabetes and obesity, of which tirzepatide is a novel dual GLP-1RA/GIPR agonist
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At present, only about 55% of commercial employers provide coverage for GLP-1 obesity therapies, while nearly 15% have already reduced or eliminated coverage because of escalating treatment costs
Firstly, the roles of GSH in cancer cells are introduced to demonstrate the importance of GSH exhaustion in anticancer therapy
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