dysesthesia tirzepatide What is the appropriate evaluation and management of new peripheral paresthesia and pruritus after starting (Mounjaro) for diabetes? Switching from tirzepatide to retatrutide:

Side effects typically become less bothersome or resolve entirely

doi:10.1016/j.jmb.2008.06.083

Neurotrophic and neuroprotective effects of oxyntomodulin in neuronal cells and a rat model of stroke

Corner TP, Tumber A, Salah E, Jabbary M, Nakashima Y, Schnaubelt LI, Basak S, Alshref FM, Brewitz L, Schofield CJ (2025) Derivatives of the clinically used HIF prolyl hydroxylase inhibitor desidustat are efficient inhibitors of human -butyrobetaine hydroxylase

If symptoms are severe or persistent, dose escalation should be delayed or the dose reduced temporarily

The 25 to 30 days after your final injection represent a critical window