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Take depemokimab (brand name Exdensur), a recently approved IL-5 inhibitor for severe asthma: patients need only two doses a year, a dramatic departure from the fortnightly or monthly routines of standard biologics

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For instance, it has been reported that hypothyroidism-induced dysfunction of the mitochondrial respiratory chain is associated with increased production of free radicals (59) Thus, excess TSH in hypothyroidism may modulate oxidative stress processes (60) by augmenting the accumulation of ROS that result from both increased generation of free radicals and diminished capacity of the antioxidative defense systems

AOD 9604 is sometimes discussed for patients who do not tolerate GLP-1 medications, a decision best made with a provider