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Oxidative stress induces a form of programmed cell death with characteristics of both apoptosis and necrosis in neuronal cells

[DOI] [PMC free article] [PubMed] [Google Scholar] 2.Edens NK, Leibel RL, Hirsch J

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479 Another cascade linking astrocytes to the pathophysiology of Down syndrome is an increased production of hydrogen sulphide, which is catalysed by cystathionine--synthase expressed, more or less exclusively, in astrocytes, and upregulated in a rat model of the disease

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