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The leaked USADA report said athletes were given infusions of the chemical L-carnitine, a naturally-produced amino acid prescribed as a supplement for heart and muscle disorders - it is not a banned substance for athletes, but infusions of more than 50 millilitres in the space of six hours are prohibited
The mitochondrial-derived peptide MOTS-c is a regulator of plasma metabolites and enhances insulin sensitivity
Many menopausal women respond well to GLP-1 therapy
The proposed direct vascular mechanisms, supported by preclinical and clinical data, include the following: Endothelial protection: GLP-1 receptor agonists promote nitric oxide production, vasodilation, and angiogenesis while inhibiting oxidative stress in vascular endothelial cells Plaque stabilization: Reduced matrix metalloproteinase activity prevents fibrous cap degradation
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