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On the cognitive side, brain fog, slower reaction time, difficulty concentrating, and headaches are common

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A buildup of ROS such as H 2 O 2 (hydrogen peroxide) and O 2 - (superoxide anion) can lead to changes in metal homeostasis or oxidation states of protein metal complexes, such as the release of Fe from ferratin or the reduction of iron in cytochrome C [119]

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(1979).Neoplastic and nonneoplastic lesions in aging (C57BL/6N x C3H/HeN)F1 (B6C3F1) mice