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GLP-1 and analogs increase glucose consumption in mature cells whereas they reduce it in progenitor cells and ADSCs, which can lead to decreased production of ATP and energy deficiency
Acetyl-L-carnitine is an acetyl ester of L-carnitine, which is synthesized in the body from the amino acid carnitine
Studies have found that there is an increase of phosphorylated MAP1B bound LC3 in Lurcher mice, which leads to the presence of high numbers of LC3-labeled autophagosomes in the axon terminals of PCs [81, 97]