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In the EXAMI study, Bernink et al

The American Diabetes Association guidelines support continued use of medications that effectively manage blood glucose and provide additional benefits such as weight loss and cardiovascular protection, with regular reassessment of treatment goals and tolerability

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Discuss Side Effects GLP-1s may cause side effects early on and throughout treatment

PMID: 4 PopovJFarbodYChauhanUKalantarMHillLArmstrongDet al

In an experimental study conducted by Noyan-Ashraf and colleagues, Liraglutide upregulated the independent expression of cardioprotective genes, including Akt, PPAR-, Nrf-2, and HO-1, while suppressing the expression of GSK3 and activation of caspase-3 in murine hearts [56]