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This effect occurs without changes in fusion protein expression or mitochondrial number and is attributed to enhanced SIRT3 activity, which promotes SOD2 deacetylation and indirectly inhibits kinases that phosphorylate DRP1 at Ser616 68

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Water Retention or Swelling: Mild edema may develop in some cases due to localized tissue repair activity

Mol Biochem Parasitol 39:155161