Keap1 regulates the oxidation-sensitive shuttling of Nrf2 into and out of the nucleus via a Crm1-dependent nuclear export mechanism
Patients pursuing GLP-1 therapy often face a critical challenge: achieving weight loss while preserving lean muscle mass
DPP-4 inhibitor therapy and bone fractures in people with Type 2 diabetesa systematic review and meta-analysis
Zheng P, Zeng B, Zhou C, Liu M, Fang Z, Xu X, et al
They demonstrate that a murine model of diabetes is associated with the development of ER stress in beta cells
Another meta-analysis found that 80% of patients infected with SARS-CoV-2 had one or more long-term symptoms and that the top most typical symptoms were chronic fatigue (58%), headache (44%), attention problems (27%), hair loss (25%), and dyspnea (24%), although memory loss, anxiety, depression, insomnia, digestive disorders, and autonomic symptoms were also widespread (from 10 to 20%) 15110 days after virus infection [106]