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The results showed that in the SUSTAIN 3, 7, and 10 trials, nausea/vomiting during dose escalation or throughout treatment contributed minimally ( 65 years), and baseline cardiovascular risk profile (prior myocardial infarction or stroke vs no prior MI or stroke, and established cardiovascular disease vs CV risk factors alone, including chronic kidney disease)

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As obesity management evolves, semaglutide represents a shift away from temporary fixes and toward evidence-based, long-term health strategies

Our results extend this understanding by showing that conjugated primary and secondary BAs are associated with mental health outcomes

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b The level of evidence was assessed using the Grading of Recommendations, Assessment, Development, and Evaluations (GRADE) or specific criteria by the individual meta-analysis