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High-fat diets, especially those rich in saturated fats, can induce inflammation by mimicking lipopolysaccharide (LPS) actions, triggering inflammatory responses via receptors on macrophages and innate immune cells

These can include nausea, vomiting, diarrhoea, constipation, abdominal pain, flatulence, gaseous distension and heartburn

Poor Diet : Diets low in nutrients can hinder the synthesis of glutathione

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The male had a smaller kidney (4.5 cm long and weighed 15.3 g) and normal-sized the other kidney (7.5 cm and 55.6 g)

Zileuton-mediated inhibition of 5-LOX reduces ROS-induced lipid peroxidation, mitochondrial damage, DNA damage, and iron-related toxicity, as verified by in vitro experiments and animal models of dry AMD